BDBM50033762 Gallinamide A

SMILES CC[C@H](C)[C@H](N(C)C)C(=O)O[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)\C=C\C(=O)N1[C@@H](C)C(OC)=CC1=O

InChI Key InChIKey=ASRBKZHDORPEHO-KYJIWOQOSA-N

Data  3 KI  19 IC50  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033762   

TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataKi:  117nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human Cathepsin B using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human Cathepsin B using Z-Phe-Arg-aminomethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed